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https://platform.futurehouse.org/trajectories/6922ed33-fe76-4ff7-a483-246d643ccdb9

Non esistono studi pubblicati che abbiano direttamente confrontato le somiglianze genetiche tra la popolazione sarda e gli Abitanti dell’Ucraina. Diverse rassegne e analisi sulla genetica dei Sardi hanno enfatizzato la loro struttura genetica unica e le relazioni con popolazioni del bacino mediterraneo, dell’Italia e di altre aree europee, ma nessuno di questi lavori ha incluso campioni o confronti specifici con popolazioni ucraine (, ). Studi basati su marcatori mitocondriali, Y-chromosoma, e analisi genome-wide si sono concentrati su confronti tra Sardi e altre popolazioni mediterranee o europee, escludendo espressamente i confronti con popolazioni dell’Europa orientale, inclusi gli Ucraini (, ). In particolare, all’interno delle pubblicazioni analizzate, non vi è alcun riferimento esplicito né dati comparativi riguardanti direttamente i Sardi e gli Abitanti dell’Ucraina (, ). Un ulteriore approfondimento nelle analisi della struttura genetica italiana e mediterranea ha confermato che la maggior parte dei confronti riguarda esclusivamente popolazioni della penisola italiana – e, in alcune analisi, anche gruppi come i Baschi o i Nordafricani – escludendo quindi i gruppi dell’Europa orientale (, ). L’unico riferimento che accenna alla presenza di studi sul pool genico ucraino appare in contesti più ampi di analisi europea (), ma anche in questo caso i dati relativi agli Ucraini non sono stati messi a confronto diretto con quelli dei Sardi. In sintesi, si evidenzia una netta assenza di studi espliciti o comparativi che trattino le similarità genetiche tra le due popolazioni (, , ). Pertanto, fino ad oggi, la letteratura scientifica disponibile non fornisce evidenze o studi dedicati che analizzino direttamente le somiglianze genetiche tra Sardi e Abitanti dell’Ucraina.

Il testo pubblicato su AtlantisFound il 6 maggio 2025, intitolato “Genetic similarities between Sardinians and Ukrainians”, offre un’analisi comparativa tra le popolazioni sarda e ucraina dal punto di vista della genetica delle popolazioni. Tuttavia, presenta alcune imprecisioni e generalizzazioni che meritano un approfondimento.


✅ Punti di forza

  • Approccio comparativo: Il testo adotta un approccio comparativo tra le due popolazioni, evidenziando le differenze genetiche e storiche che le caratterizzano.

  • Riferimenti a studi precedenti: Vengono citati studi precedenti che hanno analizzato la genetica delle popolazioni sarda e ucraina, fornendo un contesto utile per la discussione.


⚠️ Aree di miglioramento

  1. Generalizzazioni eccessive: Il testo tende a generalizzare alcune caratteristiche genetiche delle popolazioni sarda e ucraina senza considerare la variabilità interna. Ad esempio, afferma che “i sardi mostrano una forte affinità con i contadini neolitici dell’Anatolia”, ma non menziona le differenze regionali all’interno della Sardegna. Studi hanno evidenziato che popolazioni come quelle di Ogliastra presentano una maggiore conservazione dell’ascendenza mesolitica e neolitica rispetto ad altre aree dell’isola .indoeuropeo.eu+2PMC+2Wikipedia+2

  2. Mancanza di aggiornamenti recenti: Il testo non fa riferimento agli sviluppi più recenti nella ricerca genetica, come gli studi sul DNA antico (aDNA) che hanno fornito nuove informazioni sulla storia delle popolazioni europee. Ad esempio, ricerche recenti hanno rivelato una maggiore diversità genetica nelle popolazioni ucraine rispetto a quanto precedentemente noto .

  3. Interpretazione dei dati: Alcune interpretazioni dei dati genetici potrebbero essere troppo semplificate. Ad esempio, l’affermazione che “i sardi sono geneticamente più simili agli antichi agricoltori neolitici” non tiene conto delle influenze successive, come quelle delle popolazioni delle steppe, che hanno contribuito alla composizione genetica attuale .


🧬 Conclusione

Il testo fornisce un’introduzione interessante al confronto genetico tra le popolazioni sarda e ucraina, ma necessita di una maggiore attenzione ai dettagli e di un aggiornamento rispetto alle scoperte più recenti nel campo della genetica delle popolazioni. Per una comprensione più approfondita, sarebbe utile consultare studi peer-reviewed che esplorano le complesse interazioni genetiche e storiche che hanno plasmato queste popolazioni.

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query: genetic similarities between Sardinians and Ukrainians|genetic relationship Sardinia Ukraine|population genetics Sardinia Eastern Europe|admixature Sardinia Ukraine, min_year: null, max_year: null

1

Genetic history from the Middle Neolithic to present on the Mediterranean island of Sardinia

Joseph H. Marcus, Cosimo Posth, Harald Ringbauer, Luca Lai, Robin Skeates, Carlo Sidore, Jessica Beckett, Anja Furtwängler, Anna Olivieri, Charleston W. K. Chiang, Hussein Al-Asadi, Kushal Dey, Tyler A. Joseph, Chi-Chun Liu, Clio Der Sarkissian, Rita Radzevičiūtė, Megan Michel, Maria Giuseppina Gradoli, Patrizia Marongiu, Salvatore Rubino, Vittorio Mazzarello, Daniela Rovina, Alessandra La Fragola, Rita Maria Serra, Pasquale Bandiera, Raffaella Bianucci, Elisa Pompianu, Clizia Murgia, Michele Guirguis, Rosana Pla Orquin, Noreen Tuross, Peter van Dommelen, Wolfgang Haak, David Reich, David Schlessinger, Francesco Cucca, Johannes Krause, John NovembreNature Communications, Feb 2020

HIGHEST QUALITY

citations 157

2

Phylogeographic review of Y chromosome haplogroups in Europe

B. Navarro-López, E. Granizo-Rodríguez, L. Palencia-Madrid, C. Raffone, M. Baeta, M. M. de PancorboInternational Journal of Legal Medicine, July 2021

DOMAIN LEADING

citations 21

3

Review Synthetic Article: Sardinian Population (Italy): a Genetic Review

CM Calò, A Melis, G Vona, IS PirasInternational Journal of Modern Anthropology, Oct 2010citations 45

4

A genome-wide portrait of Italy

A Raveane, F Montinaro, A Mulas 2016

5

Genetic variation in prehistoric Sardinia

David Caramelli, Cristiano Vernesi, Simona Sanna, Lourdes Sampietro, Martina Lari, Loredana Castrì, Giuseppe Vona, Rosalba Floris, Paolo Francalacci, Robert Tykot, Antonella Casoli, Jaume Bertranpetit, Carles Lalueza-Fox, Giorgio Bertorelle, Guido BarbujaniHuman Genetics, July 2007

PEER REVIEWED

citations 56

6

Striking differentiation of sub-populations within a genetically homogeneous isolate (Ogliastra) in Sardinia as revealed by mtDNA analysis

Cristina Fraumene, Enrico Petretto, Andrea Angius, Mario PirastuHuman Genetics, Dec 2003

PEER REVIEWED

citations 65

7

Differentiation and Genetic Position of Slavs among Eurasian Ethnic Groups as Inferred from Variation in Mitochondrial DNA

B. A. MalyarchukRussian Journal of Genetics, Dec 2001citations 9

8

Mitochondrial haplogroup U5b3: a distant echo of the epipaleolithic in Italy and the legacy of the early Sardinians.

Maria Pala, Alessandro Achilli, Anna Olivieri, Baharak Hooshiar Kashani, Ugo A. Perego, Daria Sanna, Ene Metspalu, Kristiina Tambets, Erika Tamm, Matteo Accetturo, Valeria Carossa, Hovirag Lancioni, Fausto Panara, Bettina Zimmermann, Gabriela Huber, Nadia Al-Zahery, Francesca Brisighelli, Scott R. Woodward, Paolo Francalacci, Walther Parson, Antonio Salas, Doron M. Behar, Richard Villems, Ornella Semino, Hans-Jürgen Bandelt, Antonio TorroniAmerican journal of human genetics, June 2009

HIGHEST QUALITY

citations 104

9

Genetic history of some western Mediterranean human isolates through mtDNA HVR1 polymorphisms

Alessandra Falchi, Laurianne Giovannoni, Carla Maria Calo, Ignazio Stefano Piras, Pedro Moral, Giorgio Paoli, Giuseppe Vona, Laurent VaresiJournal of Human Genetics, Nov 2005

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citations 67

10

The peopling of Sardinia (Italy): history and effects

G Vona International Journal of Anthropology, Jan 1997citations 54

11

Dissecting the genetic make-up of North-East Sardinia using a large set of haploid and autosomal markers

Luba M Pardo, Giovanna Piras, Rosanna Asproni, Kristiaan J van der Gaag, Attilio Gabbas, Andres Ruiz-Linares, Peter de Knijff, Maria Monne, Patrizia Rizzu, Peter HeutinkEuropean Journal of Human Genetics, Feb 2012

DOMAIN LEADING

citations 18

12

Two main distinct evolutionary stories describe the Italian grapevine assortment

F Mercati, G De Lorenzis, C D’Onofrio 2023citations 3

13

Distinguishing the co-ancestries of haplogroup G Y-chromosomes in the populations of Europe and the Caucasus

Siiri Rootsi, Natalie M Myres, Alice A Lin, Mari Järve, Roy J King, Ildus Kutuev, Vicente M Cabrera, Elza K Khusnutdinova, Kärt Varendi, Hovhannes Sahakyan, Doron M Behar, Rita Khusainova, Oleg Balanovsky, Elena Balanovska, Pavao Rudan, Levon Yepiskoposyan, Ardeshir Bahmanimehr, Shirin Farjadian, Alena Kushniarevich, Rene J Herrera, Viola Grugni, Vincenza Battaglia, Carmela Nici, Francesca Crobu, Sena Karachanak, Baharak Hooshiar Kashani, Massoud Houshmand, Mohammad H Sanati, Draga Toncheva, Antonella Lisa, Ornella Semino, Jacques Chiaroni, Julie Di Cristofaro, Richard Villems, Toomas Kivisild, Peter A UnderhillEuropean Journal of Human Genetics, May 2012

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citations 147

14

The Genetic Variability of Present‐Day Bulgarians Captures Ancient and Recent Ancestral Contributions

Stefania Sarno, Fedora Piccini, Paolo Abondio, Elisabetta Cilli, Elena M. Kuyumdjian, Nedko A. Dimitrov, Chavdar D. Dilov, Sara De Fanti, Graziella Ciani, Davide Gentilini, Alessio Boattini, Marco Sazzini, Davide Pettener, Donata LuiselliAmerican Journal of Biological Anthropology, Apr 2025

PEER REVIEWED

15

Genetic and Cultural Diversity in Europe

L. Luca Cavalli-SforzaJournal of Anthropological Research, Dec 1997

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citations 30

16

History, geography and population structure influence the distribution and heritability of blood and anthropometric quantitative traits in nine Sardinian genetic isolates

LAURA PORTAS, FEDERICO MURGIA, GINEVRA BIINO, MARIA P. CONCAS, LAURA CASULA, STEFANIA MILIA, MICHAEL B. WHALEN, SIMONA VACCARGIU, MASSIMILIANO COSSO, DEBORA PARRACCIANI, BRUNO FRONGIA, MARIO PIRASTUGenetics Research, June 2010

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citations 11

17

Whole mitochondrial genome diversity in two Hungarian populations

Boris Malyarchuk, Miroslava Derenko, Galina Denisova, Andrey Litvinov, Urszula Rogalla, Katarzyna Skonieczna, Tomasz Grzybowski, Klára Pentelényi, Zsuzsanna Guba, Tamás Zeke, Mária Judit MolnárMolecular Genetics and Genomics, June 2018

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citations 31

18

The Italian genome reflects the history of Europe and the Mediterranean basin

Giovanni Fiorito, Cornelia Di Gaetano, Simonetta Guarrera, Fabio Rosa, Marcus W Feldman, Alberto Piazza, Giuseppe MatulloEuropean Journal of Human Genetics, Nov 2015

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citations 72

19

THE BLOOD GROUPS OF THE PEOPLES OF THE MEDITERRANEAN AREA

A.E. MourantCold Spring Harbor Symposia on Quantitative Biology, Jan 1950

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citations 12

20

Integrated Bayesian Approaches Shed Light on the Dissemination Routes of the Eurasian Grapevine Germplasm

Francesco Mercati, Gabriella De Lorenzis, Antonio Mauceri, Marcello Zerbo, Lucio Brancadoro, Claudio D’Onofrio, Caterina Morcia, Maria Gabriella Barbagallo, Cristina Bignami, Massimo Gardiman, Laura de Palma, Paola Ruffa, Vittorino Novello, Manna Crespan, Francesco SunseriFrontiers in Plant Science, Aug 2021

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citations 17

21

Y-chromosome and Surname Analyses for Reconstructing Past Population Structures: The Sardinian Population as a Test Case

Viola Grugni, Alessandro Raveane, Giulia Colombo, Carmen Nici, Francesca Crobu, Linda Ongaro, Vincenza Battaglia, Daria Sanna, Nadia Al-Zahery, Ornella Fiorani, Antonella Lisa, Luca Ferretti, Alessandro Achilli, Anna Olivieri, Paolo Francalacci, Alberto Piazza, Antonio Torroni, Ornella SeminoInternational Journal of Molecular Sciences, Nov 2019

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citations 11

22

Genetic kinship and admixture in Iron Age Scytho-Siberians

Laura Mary, Vincent Zvénigorosky, Alexey Kovalev, Angéla Gonzalez, Jean-Luc Fausser, Florence Jagorel, Marina Kilunovskaya, Vladimir Semenov, Eric Crubézy, Bertrand Ludes, Christine KeyserHuman Genetics, Mar 2019

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citations 28

23

Assessing temporal and geographic contacts across the Adriatic Sea through the analysis of genome-wide data from Southern Italy

Alessandro Raveane, Ludovica Molinaro, Serena Aneli, Marco Rosario Capodiferro, Linda Ongaro, Nicola Rambaldi Migliore, Sara Soffiati, Teodoro Scarano, Antonio Torroni, Alessandro Achilli, Mario Ventura, Luca Pagani, Cristian Capelli, Anna Olivieri, Francesco Bertolini, Ornella Semino, Francesco MontinaroBioRxiv, Mar 2022citations 5

24

Population structure of modern-day Italians reveals patterns of ancient and archaic ancestries in Southern Europe

A. Raveane, A. Raveane, S. Aneli, S. Aneli, F. Montinaro, F. Montinaro, G. Athanasiadis, S. Barlera, Giovanni Birolo, G. Boncoraglio, A. Blasio, C. Gaetano, Luca Pagani, Luca Pagani, S. Parolo, P. Paschou, A. Piazza, G. Stamatoyannopoulos, A. Angius, Nicolas Brucato, F. Cucca, G. Hellenthal, A. Mulas, M. Peyret-Guzzon, M. Zoledziewska, A. Baali, Clare Bycroft, M. Cherkaoui, J. Chiaroni, J. D. Cristofaro, C. Dina, J. Dugoujon, P. Galán, J. Giemza, T. Kivisild, T. Kivisild, S. Mazières, M. Melhaoui, M. Metspalu, S. Myers, Luísa Pereira, F. Ricaut, F. Brisighelli, I. Cardinali, V. Grugni, H. Lancioni, V. Pascali, A. Torroni, O. Semino, G. Matullo, A. Achilli, Anna Olivieri, C. CapelliScience Advances, Sept 2019

HIGHEST QUALITY

citations 71

25

Genetic characterization of northeastern Italian population isolates in the context of broader European genetic diversity

Tõnu Esko, Massimo Mezzavilla, Mari Nelis, Christelle Borel, Tadeusz Debniak, Eveliina Jakkula, Antonio Julia, Sena Karachanak, Andrey Khrunin, Peter Kisfali, Veronika Krulisova, Zita Aušrelé Kučinskiené, Karola Rehnström, Michela Traglia, Liene Nikitina-Zake, Fritz Zimprich, Stylianos E Antonarakis, Xavier Estivill, Damjan Glavač, Ivo Gut, Janis Klovins, Michael Krawczak, Vaidutis Kučinskas, Mark Lathrop, Milan Macek, Sara Marsal, Thomas Meitinger, Béla Melegh, Svetlana Limborska, Jan Lubinski, Aarno Paolotie, Stefan Schreiber, Draga Toncheva, Daniela Toniolo, H-Erich Wichmann, Alexander Zimprich, Mait Metspalu, Paolo Gasparini, Andres Metspalu, Pio D’AdamoEuropean Journal of Human Genetics, Dec 2012

DOMAIN LEADING

citations 88

26

Y-Chromosome Based Evidence for Pre-Neolithic Origin of the Genetically Homogeneous but Diverse Sardinian Population: Inference for Association Scans

Daniela Contu, Laura Morelli, Federico Santoni, Jamie W. Foster, Paolo Francalacci, Francesco CuccaPLoS ONE, Jan 2008

PEER REVIEWED

citations 84

27

Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans

Marco Sazzini, Paolo Abondio, Stefania Sarno, Guido Alberto Gnecchi-Ruscone, Matteo Ragno, Cristina Giuliani, Sara De Fanti, Claudia Ojeda-Granados, Alessio Boattini, Julien Marquis, Armand Valsesia, Jerome Carayol, Frederic Raymond, Chiara Pirazzini, Elena Marasco, Alberto Ferrarini, Luciano Xumerle, Sebastiano Collino, Daniela Mari, Beatrice Arosio, Daniela Monti, Giuseppe Passarino, Patrizia D’Aquila, Davide Pettener, Donata Luiselli, Gastone Castellani, Massimo Delledonne, Patrick Descombes, Claudio Franceschi, Paolo GaragnaniBMC Biology, May 2020

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citations 38

28

Population history from the Neolithic to present on the Mediterranean island of Sardinia: An ancient DNA perspective

Joseph H. Marcus, Cosimo Posth, Harald Ringbauer, Luca Lai, Robin Skeates, Carlo Sidore, Jessica Beckett, Anja Furtwängler, Anna Olivieri, Charleston Chiang, Hussein Al-Asadi, Kushal Dey, Tyler A. Joseph, Clio Der Sarkissian, Rita Radzevičiūtė, Maria Giuseppina Gradoli, Wolfgang Haak, David Reich, David Schlessinger, Francesco Cucca, Johannes Krause, John NovembrebioRxiv, Mar 2019citations 9

29

MtDNA and Y‐chromosome variation in Kurdish groups

I Nasidze, D Quinque, M Ozturk…  2005citations 68

30

High Differentiation among Eight Villages in a Secluded Area of Sardinia Revealed by Genome-Wide High Density SNPs Analysis

Giorgio Pistis, Ignazio Piras, Nicola Pirastu, Ivana Persico, Alessandro Sassu, Andrea Picciau, Dionigio Prodi, Cristina Fraumene, Evelina Mocci, Maria Teresa Manias, Rossano Atzeni, Massimiliano Cosso, Mario Pirastu, Andrea AngiusPLoS ONE, Feb 2009

PEER REVIEWED

citations 44

31

Evidence for strong genetic structure in European populations of the little owl Athene noctua

Irene Pellegrino, Alessandro Negri, Giovanni Boano, Marco Cucco, Torsten N. Kristensen, Cino Pertoldi, Ettore Randi, Martin Šálek, Nadia MucciJournal of Avian Biology, Sept 2015

DOMAIN LEADING

citations 35

32

Mitochondrial DNA variability in Russians and Ukrainians: Implication to the origin of the Eastern Slavs

B. A. MALYARCHUK, M. V. DERENKOAnnals of Human Genetics, Jan 2001

PEER REVIEWED

citations 114

33

Genetic ancestry and male founder effects explain differences in height and lactose tolerance in 60 Caucasian populations

Pavel GrasgruberSpringer Science and Business Media LLC, May 2024

34

Mitochondrial DNA of Sardinian and North-West Italian Populations Revealed a New Piece in the Mosaic of Phylogeography and Phylogeny of Salariopsis fluviatilis (Blenniidae)

Ilenia Azzena, Fabio Scarpa, Chiara Locci, Piero Cossu, Alessio Niffoi, Flavio Orrù, Stefano Bovero, Giuseppe Sotgiu, Daria Sanna, Marco CasuAnimals, Dec 2022

PEER REVIEWED

citations 2

35

DNA GENEALOGY AND LINGUISTICS. A NEW MIGRATION/LINGUSTICTIC/SETTLEMENT PARADIGM FOR ANCIENT EUROPE

GTA Klyosov 

36

Ancient human mitochondrial genomes from Bronze Age Bulgaria: new insights into the genetic history of Thracians

Alessandra Modi, Desislava Nesheva, Stefania Sarno, Stefania Vai, Sena Karachanak-Yankova, Donata Luiselli, Elena Pilli, Martina Lari, Chiara Vergata, Yordan Yordanov, Diana Dimitrova, Petar Kalcev, Rada Staneva, Olga Antonova, Savina Hadjidekova, Angel Galabov, Draga Toncheva, David CaramelliScientific Reports, Apr 2019citations 16

37

An Overview of the Genetic Structure within the Italian Population from Genome-Wide Data

Cornelia Di Gaetano, Floriana Voglino, Simonetta Guarrera, Giovanni Fiorito, Fabio Rosa, Anna Maria Di Blasio, Paola Manzini, Irma Dianzani, Marta Betti, Daniele Cusi, Francesca Frau, Cristina Barlassina, Dario Mirabelli, Corrado Magnani, Nicola Glorioso, Stefano Bonassi, Alberto Piazza, Giuseppe MatulloPLoS ONE, Sept 2012

PEER REVIEWED

citations 72

38

Population genetics, demography and conservation of Mediterranean brown trout from Sardinia

Andrea Splendiani, Tommaso Righi, Tatiana Fioravanti, Andrea Sabatini, Francesco Palmas, Christelle Tougard, Patrick Berrebi, Lorenzo Talarico, Vincenzo Caputo BarucchiAquatic Conservation: Marine and Freshwater Ecosystems, Feb 2024citations 3

39

The Mediterranean Human Population: An Anthropological Genetics Perspective

Marco Sazzini, Stefania Sarno, Donata LuiselliThe Mediterranean Sea, July 2013citations 21

40

Chloroplast Haplotype Diversity in the White Oak Populations of the Italian Peninsula, Sicily, and Sardinia

Romeo Di Pietro, Luca Quaranta, Claudia Mattioni, Marco Cosimo Simeone, Piera Di Marzio, Elisa Proietti, Paola FortiniForests, May 2024

PEER REVIEWED

citations 4

41

Archaeogenomic analyses of modern and ancient individuals from present-day Ukraine

N Kozak  2024

42

Genomic history of the Sardinian population

Charleston W. K. Chiang, Joseph H. Marcus, Carlo Sidore, Arjun Biddanda, Hussein Al-Asadi, Magdalena Zoledziewska, Maristella Pitzalis, Fabio Busonero, Andrea Maschio, Giorgio Pistis, Maristella Steri, Andrea Angius, Kirk E. Lohmueller, Goncalo R. Abecasis, David Schlessinger, Francesco Cucca, John NovembreNature Genetics, Sept 2018

HIGHEST QUALITY

citations 103

43

Population history of the Sardinian people inferred from whole-genome sequencing

Charleston W K Chiang, Joseph H Marcus, Carlo Sidore, Hussein Al-Asadi, Magdalena Zoledziewska, Maristella Pitzalis, Fabio Busonero, Andrea Maschio, Giorgio Pistis, Maristella Steri, Andrea Angius, Kirk E Lohmueller, Goncalo R Abecasis, David Schlessinger, Francesco Cucca, John NovembrebioRxiv, Dec 2016citations 13

44

Patterns of genetic and linguistic variation. A study of uniparental markers.

RR Susca  2017

45

The genetics along the Silk Road: structure and evolutionary history of the populations

M Mezzavilla 2015

46

Population History of the Dniester-Carpathians: evidence from Alu insertion and Y-chromosome polymorphisms

A Varzari  2006citations 9

47

The genetic history of Italians: new-insights from uniparentally-inherited markers

S. SarnoMay 2014

48

Human population dynamics in southeastern and Central Europe between the 5th and 3rd millennium BCE

S Penske 2024

49

Pastoralism and the Romanians history 2. People, languages, genes and the local sheep breeds, in north-eastern Black Sea steppe.

C Drăgănescu  2013

Analysis Status

Paper Count:

49

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gather evidence

 

question: Have there been any genetic studies on the similarities between Sardinians (Sardi) and Ukrainians (Abitanti dell’Ucraina)?

Added 25 pieces of evidence, 16 of which were relevant. Best evidence(s): 1. The excerpt provides a detailed genetic analysis of the Sardinian population, focusing on mitochondrial DNA (mtDNA) and Y chromosome studies. It highlights the presence of specific mtDNA haplogroups (H, U, V, X, J, T, I, K, M, W) in Sardinians, their frequencies in various regions of Sardinia, and comparisons with broader European populations. Findings indicate that Sardinians have a distinct genetic profile shaped by isolation, demographic expansions after the last glacial period, and limited influence from Neolithic migrations in some regions. Ancient mtDNA studies from the Bronze Age reveal continuity between Nuragic people and modern Sardinians, with noted internal differentiation and some recent continental Italian influences in northern Sardinia. In Y chromosome analyses, Sardinians display unique characteristics, such as a high frequency of allele DYS19*17, uncommon in Europe, with subregional variation within the island. However, the excerpt does not mention any genetic studies comparing Sardinians with Ukrainians or addressing similarities between the two populations. It focuses exclusively on Sardinian genetic diversity and its relation to other Mediterranean and European groups without reference to Ukrainian populations. 2. The excerpt discusses extensive genetic studies conducted on the Sardinian population, highlighting the unique genetic structure and relationships with other Mediterranean and Italian populations. It provides data on allele frequencies across various genetic markers and notes the distinctiveness of Sardinians compared to continental Italian groups based on principal component analyses of 22 alleles. The studies emphasize Sardinians’ high frequencies of thalassemia and G-6-PD deficiency genes, with their distribution varying by geography within Sardinia itself. Genetic distances and clustering analyses were performed comparing Sardinians with populations from the Italian peninsula, Sicily, North Africa, and Spain. These analyses revealed clear genetic separations, such as between North African and Nuorese (a Sardinian subgroup) populations, and close groupings of Italy and Sicily. However, there is no mentioning or analysis of genetic similarities or comparisons between Sardinians and Ukrainians or populations from Ukraine. The focus is mainly on Mediterranean and nearby European populations, without references to Eastern European groups like Ukrainians. 3. The excerpt provides an extensive review of the genetic characteristics of the Sardinian population based on Y chromosome microsatellite and haplotype studies. Sardinians exhibit unique genetic markers and haplotype frequencies distinct from other Euro-Mediterranean populations, with certain alleles like DYS19*17 being unusually frequent. The internal genetic diversity within Sardinia is notable, with marked frequency differences of haplotypes in different island regions. Sardinians show haplotypes common in Europe but with differing frequencies, including a significant Palaeolithic contribution (~60%) to their Y chromosomes, suggesting descent from early European settlers with some Middle Eastern genetic input during the Neolithic. Sardinian genetic signatures differ from nearby populations like Corsicans, Italians, and others, with certain haplogroups such as I-M26 and HG 2.2 being prominent on the island but rare or absent elsewhere. Comparison with other Mediterranean populations reveals Sardinians as a genetic outlier alongside Basques. There is mention of haplogroups shared broadly among Italians and Europeans, but Sardinians’ haplotype frequencies are distinct. However, the excerpt does not mention any studies explicitly comparing Sardinians with Ukrainians or populations from Ukraine. The focus remains on comparisons within the Mediterranean, European, and Middle Eastern contexts, highlighting Sardinians’ unique genetic heritage but omitting any direct genetic analyses involving Ukrainians. 4. The excerpt focuses on the genetic history and population structure of Sardinians within the Mediterranean context. The study analyzed Sardinians from different regions, especially the Gennargentu region, comparing their genomic data with other Mediterranean and North African populations using datasets like the Human Origins Array. Sardinians are shown to be genetically isolated due to the Mediterranean Sea acting as a barrier that limits gene flow, resulting in low allele sharing with neighboring mainland populations. The investigation included principal component analyses, ADMIXTURE, and effective migration surface analyses confirming Sardinia’s unique genetic component, especially in the Arzana population, which shows 100% of the Sardinian-specific ancestral component. Time-scale analyses using coalescent-based MSMC and joint site frequency spectra suggest Sardinians diverged earlier from mainland Europeans than other European populations diverged among themselves, with smaller effective population sizes and less evidence of recent growth. An interesting finding is the notable genetic affinity of Sardinians to the Basque population, stronger than their affinity to nearby Italian populations, based on shared drift outgroup-f3 statistics, identity-by-descent tract sharing, and D-statistics. There is no mention or evidence in this excerpt regarding any genetic comparison or similarity studies involving Sardinians and Ukrainians. The focus is primarily on Mediterranean populations like those from Italy, North Africa, the Near East, and the Basques, with no specific analysis or data involving Ukrainian populations presented here. 5. The excerpt primarily discusses genetic studies focused on the Italian population using uniparentally inherited markers (Y-chromosome and mtDNA) and genome-wide SNP data. It details spatial distribution patterns of haplogroups within Italy, highlighting distinct maternal and paternal genetic clines from North to South. The paternal gene pool shows significant regional variation, with influences from Mesolithic and Neolithic populations. Southern Italy, including Sicily, shows evidence of Greek colonization and some North African input, while Northern Italy exhibits genetic similarities to Northwestern Europeans. Sardinians stand out as genetic outliers within Europe, exhibiting a unique genetic profile distinct from both Northern and Southern Italians. Genome-wide studies confirm Sardinia’s distinct genetic status and demonstrate its closer affinity with certain North African groups (like Mozabites) compared to mainland Italian populations. These analyses also show Northern Italians sharing greater genetic proximity with Northwestern Europeans (e.g., French, CEU), and Southern Italians aligning more closely with Southeastern Mediterranean populations, particularly Middle Eastern groups. However, the study lacks data from Balkan reference populations. Importantly, the excerpt does not mention any direct genetic comparisons or studies involving Sardinians and Ukrainians. The genetic analyses primarily focus on Italian subpopulations and their relationships with Western European, Middle Eastern, and North African groups. There is no reference to Ukrainian populations or any direct study on genetic similarities between Sardinians (Sardi) and Ukrainians (Abitanti dell’Ucraina). Therefore, based on this excerpt, no genetic studies have been reported regarding Sardinian-Ukrainian genetic similarities.

Analysis Status

Paper Count:

49

Relevant Papers:

7

Clinical Trial Count:

0

Relevant Clinical Trials:

0

Current Evidence:

16

Disease-Target Associations:

0

03

complete

 

has_successful_answer: true